I've played the game and there's several things I want to say.
First of all, fuck Yoshi.
Okay.
I like the game a lot. It's the first game in the Dr. Mario series I've played, but I really enjoy all of the new additions to the Dr. Mario gameplay that this game provides. Alongside your typical viruses that you need to destroy with your limited amount of capsules, you have those little gimmicks in bubbles or in cages or finding coins and whatnot that really spice up the gameplay later on so that it doesn't get repetitive. Completing these puzzles and making you sit and think is a joy for me. The game can even get pretty tough early on (I wouldn't recommend tackling those challenge levels in the first world, not before you have gotten any assistants or leveled up your doctor, I've tried them and their hard-as-nails difficult, especially to get three stars on) and if you're aiming to get three stars on all levels, the game provides you the challenge to do that.
Versus mode is also pretty good. You can beat up players to get rewards at no cost of hearts (though the battle boxes also have a timer). Matchmaking is fine, and I've encountered a bug where I lost once despite my grid not being touched to the bottom for some strange reason. The game is fast and frantic, matches go and play themselves very quickly, so I found it pretty entertaining for my brief time spent there.
However, everything negative I can say about the game is attributed to its lootbox and free-to-wait energy system. Getting the character you want to be can be a real chore because you have a ridiculously small percent of getting one. I was lucky I got Dr. Toad as my second doctor, otherwise I would have been stuck with characters I don't really care for in the game. I understand that the game is free, but the game really tugs at you to get you to spend cash to clear hard levels or to refill your energy instantly, as well as playing the lottery for the character you want. If I had things my way, you should get to enjoy the game as it is, but there should also just be the option to buy the doctor you want to be straight up than pray the character or assistant you want is in the damn box.
I'd pretty much give the game a 6/10. If there was no free-to-wait economy and lootboxes, easily would have been an amazing and solid puzzle game I would recommended otherwise. Sadly, I can't recommend this to people with gambling addictions at all. It's not worth it.